对患有囊性纤维化和阻塞性睡眠呼吸暂停综合征的儿童及青少年上呼吸道的评估。
Evaluation of the upper airway in children and adolescents with cystic fibrosis and obstructive sleep apnea syndrome.
作者信息
Ramos Regina Terse Trindade, Salles Cristina, Gregório Paloma Baiardi, Barros Alessandro Tunes, Santana Angélica, Araújo-Filho José Bouzas, Acosta Angelina Xavier
机构信息
Department of Pediatrics, Federal University of Bahia School of Medicine, Bahia, Brazil.
出版信息
Int J Pediatr Otorhinolaryngol. 2009 Dec;73(12):1780-5. doi: 10.1016/j.ijporl.2009.09.037. Epub 2009 Oct 24.
OBJECTIVE
Obstructive sleep apnea syndrome (OSAS) in cystic fibrosis (CF) patients may be associated with the presence of upper airway obstruction caused by chronic infection and nasal polyposis that may also contribute to OSAS severity. Our objective was to identify the profile of findings in CF and OSAS patients by performing upper airway examinations.
METHODOLOGY
Observational, cross-sectional study involving 63 children and adolescents between the ages of 2 and 14 with CF. All patients answered a questionnaire and underwent a standard otolaryngology examination, including an endoscopic nasal and nocturnal polysomnography. OSAS diagnosis was confirmed if the obstructive apnea index was >or=1.
RESULTS
OSAS was identified in 35 (55.6%) patients. The upper airway findings were evaluated using multiple correspondence factorial analysis. The OSAS group presented with overjet >2mm, enlarged pharyngeal pillars, palatine tonsils and pharyngeal tonsils hypertrophy, ogival hard palates and characteristics of chronic rhinosinusitis.
CONCLUSION
Bone and soft tissue structural alterations of the upper airway and chronic rhinosinusitis were associated with the OSAS group patients.
目的
囊性纤维化（CF）患者的阻塞性睡眠呼吸暂停综合征（OSAS）可能与慢性感染和鼻息肉引起的上气道阻塞有关，这也可能导致OSAS的严重程度。我们的目的是通过对上气道进行检查来确定CF和OSAS患者的检查结果特征。
方法
对63名年龄在2至14岁之间的CF儿童和青少年进行观察性横断面研究。所有患者均回答了一份问卷，并接受了标准的耳鼻喉科检查，包括鼻内镜检查和夜间多导睡眠图检查。如果阻塞性呼吸暂停指数≥1，则确诊为OSAS。
结果
35名（55.6%）患者被诊断为OSAS。使用多重对应因子分析对上气道检查结果进行评估。OSAS组表现为覆盖超过2mm、咽柱增大、腭扁桃体和咽扁桃体肥大、尖拱形硬腭以及慢性鼻窦炎的特征。
结论
上气道的骨骼和软组织结构改变以及慢性鼻窦炎与OSAS组患者有关。
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