Empting L D
Independent Neurodiagnostic Clinic, Atlanta, GA 30327, USA.
Toxicol Ind Health. 2009 Oct-Nov;25(9-10):577-81. doi: 10.1177/0748233709348393.
Human exposure to molds, mycotoxins, and water-damaged buildings can cause neurologic and neuropsychiatric signs and symptoms. Many of these clinical features can partly mimic or be similar to classic neurologic disorders including pain syndromes, movement disorders, delirium, dementia, and disorders of balance and coordination. In this article, the author delineates the signs and symptoms of a syndrome precipitated by mold and mycotoxin exposure and contrasts and separates these findings neurodiagnostically from known neurologic diseases. This clinical process is designed to further the scientific exploration of the underlying neuropathophysiologic processes and to promote better understanding of effects of mold/mycotoxin/water-damaged buildings on the human nervous system and diseases of the nervous system. It is clear that mycotoxins can affect sensitive individuals, and possibly accelerate underlying neurologic/pathologic processes, but it is crucial to separate known neurologic and neuropsychiatric disorders from mycotoxin effects in order to study it properly.
人类接触霉菌、霉菌毒素和受水损害的建筑物会导致神经和神经精神方面的体征和症状。这些临床特征中的许多部分可以模仿或类似于经典的神经系统疾病，包括疼痛综合征、运动障碍、谵妄、痴呆以及平衡和协调障碍。在本文中，作者描述了由接触霉菌和霉菌毒素引发的一种综合征的体征和症状，并从神经诊断学角度将这些发现与已知的神经系统疾病进行对比和区分。这个临床过程旨在进一步科学探索潜在的神经病理生理过程，并促进对霉菌/霉菌毒素/受水损害的建筑物对人类神经系统及神经系统疾病影响的更好理解。很明显，霉菌毒素会影响敏感个体，并可能加速潜在的神经/病理过程，但为了正确研究它，将已知的神经和神经精神疾病与霉菌毒素的影响区分开来至关重要。
