• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology.

作者信息

Hebbel R P

机构信息

Department of Medicine, University of Minnesota Medical School, Minneapolis 55455.

出版信息

Blood. 1991 Jan 15;77(2):214-37.

PMID:1985689
Abstract
摘要

相似文献

1
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology.
Blood. 1991 Jan 15;77(2):214-37.
2
Viscoelastic properties of the oxygenated sickle erythrocyte membrane.氧合镰状红细胞膜的粘弹性特性
Biorheology. 1989;26(5):935-49.
3
[Structural and functional alterations of the erythrocyte membrane in sickle cell anemia].镰状细胞贫血中红细胞膜的结构和功能改变
Bull Eur Physiopathol Respir. 1983 Jul-Aug;19(4):345-50.
4
Continuous viscous deformation of red blood cells in flow and their disturbance in sickle cell disease.流动中红细胞的持续粘性变形及其在镰状细胞病中的紊乱。
Blood Cells. 1982;8(1):29-51.
5
Increased adherence of sickled and phosphatidylserine-enriched human erythrocytes to cultured human peripheral blood monocytes.镰状且富含磷脂酰丝氨酸的人红细胞与培养的人外周血单核细胞的黏附增加。
J Clin Invest. 1985 Jun;75(6):1965-72. doi: 10.1172/JCI111913.
6
Sickle cell biomechanics.镰状细胞生物力学。
Annu Rev Biomed Eng. 2010 Aug 15;12:345-67. doi: 10.1146/annurev-bioeng-070909-105339.
7
Disorders of erythrocyte cation permeability and water content associated with hemolytic anemia.与溶血性贫血相关的红细胞阳离子通透性和含水量紊乱。
Biomembranes. 1983;11:79-118.
8
Contributions of sickle hemoglobin polymer and sickle cell membranes to impaired filterability.镰状血红蛋白聚合物和镰状细胞膜对滤过性受损的作用。
Am J Physiol. 1995 May;268(5 Pt 2):H2003-8. doi: 10.1152/ajpheart.1995.268.5.H2003.
9
GBT440 improves red blood cell deformability and reduces viscosity of sickle cell blood under deoxygenated conditions.GBT440在脱氧条件下可改善镰状细胞血液的红细胞变形能力并降低其粘度。
Clin Hemorheol Microcirc. 2018;70(1):95-105. doi: 10.3233/CH-170340.
10
Influence of sickle hemoglobin polymerization and membrane properties on deformability of sickle erythrocytes in the microcirculation.镰状血红蛋白聚合和膜特性对微循环中镰状红细胞变形性的影响。
Biophys J. 1992 Sep;63(3):774-83. doi: 10.1016/S0006-3495(92)81655-7.

引用本文的文献

1
snoRNAs and : New Targets for Sickle Cell Disease Complications.小核仁RNA与：镰状细胞病并发症的新靶点
Circ Res. 2025 Jul 18;137(3):e40-e61. doi: 10.1161/CIRCRESAHA.124.325093. Epub 2025 May 15.
2
GBT1118, a voxelotor analog, protects red blood cells from damage during severe hypoxia.GBT1118是一种与voxelotor类似的药物，可在严重缺氧期间保护红细胞免受损伤。
Am J Transl Res. 2022 Jan 15;14(1):240-251. eCollection 2022.
3
Sickle Cell Anemia and Infection.镰状细胞贫血与感染
Pathogens. 2021 Nov 4;10(11):1435. doi: 10.3390/pathogens10111435.
4
Extracellular Vesicles in Sickle Cell Disease: Plasma Concentration, Blood Cell Types Origin Distribution and Biological Properties.镰状细胞病中的细胞外囊泡：血浆浓度、血细胞类型起源分布及生物学特性
Front Med (Lausanne). 2021 Aug 20;8:728693. doi: 10.3389/fmed.2021.728693. eCollection 2021.
5
assay for single-cell characterization of impaired deformability in red blood cells under recurrent episodes of hypoxia.用于在反复缺氧发作期间对红细胞变形能力受损进行单细胞特征分析的检测方法。
Lab Chip. 2021 Sep 14;21(18):3458-3470. doi: 10.1039/d1lc00598g.
6
Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia.肾髓质状况对镰状细胞贫血患者红细胞行为的病理生理相关性
Front Physiol. 2021 Mar 19;12:653545. doi: 10.3389/fphys.2021.653545. eCollection 2021.
7
Characterization and statistical modeling of glycosylation changes in sickle cell disease.镰状细胞病中糖基化变化的特征描述和统计建模。
Blood Adv. 2021 Mar 9;5(5):1463-1473. doi: 10.1182/bloodadvances.2020003376.
8
The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease.生命中最糟糕的事情是免费的：游离血红素在镰状细胞病中的作用。
Front Immunol. 2021 Jan 27;11:561917. doi: 10.3389/fimmu.2020.561917. eCollection 2020.
9
Standardized microfluidic assessment of red blood cell-mediated microcapillary occlusion: Association with clinical phenotype and hydroxyurea responsiveness in sickle cell disease.标准化微流控评估红细胞介导的微毛细血管阻塞：与镰状细胞病的临床表型和羟基脲反应性的关联。
Microcirculation. 2021 Feb;28(2):e12662. doi: 10.1111/micc.12662. Epub 2021 Jan 9.
10
Oxidative stress activates red cell adhesion to laminin in sickle cell disease.氧化应激激活镰状细胞病红细胞与层粘连蛋白的黏附。
Haematologica. 2021 Sep 1;106(9):2478-2488. doi: 10.3324/haematol.2020.261586.