Jovanović Zeljko, Crncević-Orlić Zeljka, Stimac Davor, Kokić Slaven, Persić Viktor, Ruzić Tatjana, Goll-Barić Sanda
Healthy Weight Loss Project Rijeka, Rijeka, Croatia.
Coll Antropol. 2009 Sep;33(3):751-7.
Prevention of obesity may help reduce the morbidity and mortality from cardiovascular diseases. In Croatia, over half of adult population is overweight. Aldo the basic medical principles of healthy weight-loss programmes are well known, it is believed that mainly because of the leak of successful therapeutic approach obesity remains the most challenging changeable cardiovascular risk factor in nowadays clinical practice. Objective of this Croatian Healthy Weight Loss Programme substudy was to determine effects and differences between the intensive group and intensive individual weight-loss program on weight loss and cardiovascular risk factor. A clinical trial included 476 adults whose body mass index (BMI) was > 30 or > 28 accompanied by increased blood pressure, glucose, and cholesterol. The study participants completed either a group (n = 243) or individually-based (n = 233) 6-month weight-loss program consisting of education, low-fat diet, pharmacological treatment with orlistat, psychological counselling, and exercise. Body weight, body mass index, blood pressure, blood sugar, and blood cholesterol were measured in all participants after 3 and 6 months. The average weight loss was 12.2 (13%) kg and 7.6 (9%) kg in the group and individual program, respectively. Beside the weight reduction, the levels of blood cholesterol, glucose, and blood pressure were also significantly reduced in comparison with baseline, decreasing to normal values in all participants (P < 0.001 for all). Decrease in the monitored parameters was greater in participants in the group program. The weight loss program provided a healthy loss of extra weight in the period of 6 months. The group program produced greater decrease in body weight, body mass index, blood pressure, glucose, and cholesterol than the individual program.
预防肥胖可能有助于降低心血管疾病的发病率和死亡率。在克罗地亚，超过一半的成年人口超重。尽管健康减肥计划的基本医学原则广为人知，但人们认为，主要由于缺乏成功的治疗方法，肥胖在当今临床实践中仍然是最具挑战性的可变心血管危险因素。这项克罗地亚健康减肥计划子研究的目的是确定强化组和强化个体减肥计划在体重减轻和心血管危险因素方面的效果及差异。一项临床试验纳入了476名成年人，他们的体重指数（BMI）>30或>28，并伴有血压、血糖和胆固醇升高。研究参与者完成了为期6个月的减肥计划，该计划要么是集体的（n = 243），要么是基于个体的（n = 233），包括教育、低脂饮食、用奥利司他进行药物治疗、心理咨询和运动。在3个月和6个月后对所有参与者测量体重、体重指数、血压、血糖和血胆固醇。集体计划组和个体计划组的平均体重减轻分别为12.2（13%）kg和7.6（9%）kg。除了体重减轻外，与基线相比，血胆固醇、血糖和血压水平也显著降低，所有参与者均降至正常水平（所有P<0.001）。集体计划组参与者监测参数的下降幅度更大。该减肥计划在6个月内实现了健康的额外体重减轻。集体计划组在体重、体重指数、血压、血糖和胆固醇方面的下降幅度比个体计划组更大。
