University of Manchester, Respiratory Research Group, School of Translational Medicine and NIHR, Translational Research Facility, Respiratory Medicine, Manchester.
Br J Gen Pract. 2009 Nov;59(568):839-43. doi: 10.3399/bjgp09X472890.
In order to assess and plan for changing healthcare needs, the lack of available information regarding temporal changes in the health-related quality of life of a population must be addressed.
This paper aims to describe such changes over 5 years in a general population.
Longitudinal postal questionnaire study.
UK general practice.
This was a longitudinal postal questionnaire study in two general practice populations, using the generic instrument EQ-5D to measure health-related quality of life. Individuals were included if they responded to three postal surveys in 1999, 2001, and 2004 and there were three consecutive values of EQ-5D(index) available between 1999 and 2004.
A total of 2498 subjects were included in the study. After adjustment for potential confounders (including ageing), health-related quality of life declined significantly over the observation period. The change in EQ-5D(index) was from 0.79 to 0.74 and for EQ-5D(vas) 76.8 to 73.3 (P for both trends <0.001).
Health-related quality of life deteriorated in these populations over 5 years. In an era of improvements in mortality, this has important implications for the use of health-related quality of life data in healthcare planning and resource allocation.
为了评估和规划不断变化的医疗需求，必须解决有关人群健康相关生活质量随时间变化的可用信息缺乏的问题。
本文旨在描述一般人群中 5 年内的此类变化。
纵向邮寄问卷研究。
英国全科医疗。
这是一项在两个普通科医疗人群中进行的纵向邮寄问卷研究，使用通用工具 EQ-5D 来衡量健康相关的生活质量。如果个体在 1999 年、2001 年和 2004 年回应了三次邮寄调查，并且在 1999 年至 2004 年期间有三个连续的 EQ-5D（指数）值，则将其纳入研究。
共有 2498 名受试者纳入研究。经过对潜在混杂因素（包括年龄）的调整后，观察期间健康相关生活质量显著下降。EQ-5D（指数）的变化从 0.79 降至 0.74，EQ-5D（vas）从 76.8 降至 73.3（两种趋势的 P 值均<0.001）。
这些人群的健康相关生活质量在 5 年内恶化。在死亡率提高的时代，这对医疗保健规划和资源分配中使用健康相关生活质量数据具有重要意义。
