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心脏手术和免疫抑制后发生的致命性真菌性心包炎。

Fatal fungal pericarditis after cardiac surgery and immunosuppression.

作者信息

Carrel T P, Schaffner A, Schmid E R, Schneider J, Bauer E P, Laske A, von Segesser L K, Turina M I

机构信息

Clinic for Cardiovascular Surgery, University Hospital, Zürich, Switzerland.

出版信息

J Thorac Cardiovasc Surg. 1991 Jan;101(1):161-4.

PMID:1986160
Abstract

The cases of two patients with fulminant pericarditis after cardiac surgery are reported. Both fungal infections developed after rethoracotomy for open-chest cardiac resuscitation and high-dose glucocorticoid treatment. Although the time course of both infections from the inoculation of fungi during rethoracotomy and immunosuppression with glucocorticoids to the lethal outcome was strikingly similar, histopathologic studies disclosed the disparate character of the two fungal pathogens responsible: the yeast Candida albicans and the angiotropic mold Aspergillus fumigatus.

摘要

报告了两例心脏手术后暴发性心包炎患者的病例。两例真菌感染均发生在开胸心脏复苏和大剂量糖皮质激素治疗后再次开胸手术之后。尽管从开胸手术中接种真菌以及使用糖皮质激素进行免疫抑制到致命结局的两种感染病程惊人地相似,但组织病理学研究揭示了两种致病真菌病原体的不同特征:酵母白色念珠菌和嗜血管霉菌烟曲霉。

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