急性淋巴细胞白血病合并侵袭性曲霉病和气心包，伏立康唑治疗成功。
Acute lymphocytic leukemia with superimposed invasive aspergillosis and pneumopericardium successfully treated with voriconazole.
作者信息
Alviar Carlos L, Doherty Bryan, Vaduganathan Muthiah
机构信息
Division of Cardiology, New York University Langone Medical Center, New York, NY (Alviar); Lennox Hill Hospital, New York, NY (Doherty); and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Vaduganathan).
出版信息
Proc (Bayl Univ Med Cent). 2014 Jul;27(3):250-2. doi: 10.1080/08998280.2014.11929128.
Abstract
We present a 47-year-old man with acute lymphocytic leukemia with a pericardial friction rub heralding pericardial aspergillosis. The clinical course was complicated by pneumopericardium, likely secondary to a direct connection between the lung parenchyma and the pericardial space. Bronchoalveolar lavage cultures returned positive for methicillin-resistant Staphylococcus aureus and Aspergillus niger. Combination voriconazole and vancomycin resulted in symptomatic improvement within 2 weeks of hospitalization.
摘要
我们报告一名47岁急性淋巴细胞白血病男性患者，其出现心包摩擦音，提示心包曲霉菌病。临床过程因纵隔积气而复杂化，这可能继发于肺实质与心包腔之间的直接连通。支气管肺泡灌洗培养结果显示耐甲氧西林金黄色葡萄球菌和黑曲霉呈阳性。伏立康唑和万古霉素联合使用使患者在住院2周内症状得到改善。
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