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[口腔和生殖器黏膜的人乳头瘤病毒感染。一级预防的可能性]

[HPV infections of the oral and genital mucosa. Possibilities for primary prevention].

作者信息

Kirnbauer R, Schellenbacher C, Shafti-Keramat S, Handisurya A

机构信息

Labor für Virale Onkologie (LVO), Abteilung für Immundermatologie und infektiöse Hautkrankheiten, Klinik für Dermatologie, Medizinische Universität Wien, Allgemeines Krankenhaus, 1090 Wien, Osterreich.

出版信息

Hautarzt. 2009 Nov;60(11):878-80. doi: 10.1007/s00105-009-1803-4.

DOI:10.1007/s00105-009-1803-4
PMID:19862489
Abstract

It is well accepted today that almost all cases of carcinoma of the cervix are caused by persistent infections with high-risk human papilloma viruses (HPV), especially through types HPV16 and HPV18 (ca. 70%). These same types are also responsible for some carcinomas of the vulva, anus, penis and oropharynx. This knowledge indicates that it should be possible to prevent these carcinomas if a majority of the causstive HPV infections can be prevented.

摘要

如今人们普遍认为,几乎所有宫颈癌病例都是由高危型人乳头瘤病毒(HPV)持续感染引起的,尤其是HPV16型和HPV18型(约占70%)。同样这两种类型也与一些外阴癌、肛门癌、阴茎癌和口咽癌有关。这一认知表明,如果能够预防大多数致病性HPV感染,那么就有可能预防这些癌症。

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Chimeric L1-L2 virus-like particles as potential broad-spectrum human papillomavirus vaccines.嵌合L1-L2病毒样颗粒作为潜在的广谱人乳头瘤病毒疫苗。
J Virol. 2009 Oct;83(19):10085-95. doi: 10.1128/JVI.01088-09. Epub 2009 Jul 29.
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Rapid progression of an anal Buschke-Lowenstein tumour into a metastasising squamous cell carcinoma in an HIV-infected patient.一名艾滋病病毒感染患者的肛门Buschke-Lowenstein肿瘤迅速进展为转移性鳞状细胞癌。
Sex Transm Infect. 2009 Aug;85(4):261-3. doi: 10.1136/sti.2008.034959.
3
Diseases caused by human papillomaviruses (HPV).
由人乳头瘤病毒(HPV)引起的疾病。
J Dtsch Dermatol Ges. 2009 May;7(5):453-66; quiz 466, 467. doi: 10.1111/j.1610-0387.2009.06988.x. Epub 2009 Mar 6.
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Serological relationship between cutaneous human papillomavirus types 5, 8 and 92.皮肤型人乳头瘤病毒5型、8型和92型之间的血清学关系。
J Gen Virol. 2009 Jan;90(Pt 1):136-43. doi: 10.1099/vir.0.006189-0.
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Human papillomavirus type 26 infection causing multiple invasive squamous cell carcinomas of the fingernails in an AIDS patient under highly active antiretroviral therapy.在接受高效抗逆转录病毒治疗的艾滋病患者中,26型人乳头瘤病毒感染导致指甲多发浸润性鳞状细胞癌。
Br J Dermatol. 2007 Oct;157(4):788-94. doi: 10.1111/j.1365-2133.2007.08094.x. Epub 2007 Jul 19.
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Lancet. 2007 Jun 30;369(9580):2161-2170. doi: 10.1016/S0140-6736(07)60946-5.
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