Royse Colin Forbes
Anaesthesia and Pain Management Unit, Department of Pharmacology, University of Melbourne, Carlton, VIC, Australia.
Best Pract Res Clin Anaesthesiol. 2009 Sep;23(3):273-83. doi: 10.1016/j.bpa.2009.02.009.
The haemodynamic state refers to the integration of myocardial and vascular systems, and involves both left and right hearts, and systolic and diastolic phases. The assessment of the haemodynamic state can be performed with echocardiography, and provides a higher level of diagnosis than conventional pressure- and flow-based monitoring. Whilst hypotension alerts the practitioner about the existence of haemodynamic abnormality, it does not provide sufficient information to identify the cause or the underlying haemodynamic state. The premise of haemodynamic state monitoring is that better diagnosis will lead to more rational therapy, which in turn may improve the outcome. The haemodynamic state can be classified into seven broad categories: normal, empty, vasodilation, systolic failure, primary diastolic failure, systolic and diastolic failure and right ventricular failure. These are identified as patterns based upon ventricular size, ventricular function and left atrial (LA) filling pressure. Patients may have an abnormal haemodynamic state (such a systolic failure), but may not need active treatment if they are haemodynamically stable. However, if treatment is required, it can be directed according to the underlying haemodynamic state. For example, a patient with systolic failure may benefit from inotrope support, whereas an empty state acquires volume infusion and vasodilation requires vasopressor support.
血流动力学状态指心肌和血管系统的整合,涉及左、右心以及收缩期和舒张期。血流动力学状态的评估可通过超声心动图进行,且相较于传统基于压力和流量的监测,能提供更高水平的诊断。虽然低血压会提醒从业者存在血流动力学异常,但它并未提供足够信息来确定病因或潜在的血流动力学状态。血流动力学状态监测的前提是更好的诊断将带来更合理的治疗,而这反过来可能改善预后。血流动力学状态可大致分为七大类:正常、空虚、血管扩张、收缩功能衰竭、原发性舒张功能衰竭、收缩和舒张功能衰竭以及右心室衰竭。这些是根据心室大小、心室功能和左心房充盈压确定的模式。患者可能存在异常的血流动力学状态(如收缩功能衰竭),但如果血流动力学稳定,可能无需积极治疗。然而,如果需要治疗,则可根据潜在的血流动力学状态进行指导。例如,收缩功能衰竭的患者可能受益于使用正性肌力药物支持,而空虚状态需要补充容量,血管扩张则需要血管升压药支持。