一锅法伪四组分合成螺[二茚并[1,2 - b:2',1'- e]吡啶 - 11,3'- 吲哚啉] - 三酮文库
One-pot, pseudo four-component synthesis of a spiro[diindeno[1,2-b:2',1'-e]pyridine-11,3'-indoline]-trione library.
作者信息
Ghahremanzadeh Ramin, Shakibaei Ghazaleh Imani, Ahadi Somayeh, Bazgir Ayoob
机构信息
Department of Chemistry, Shahid Beheshti University, Tehran, Iran.
出版信息
J Comb Chem. 2010 Jan-Feb;12(1):191-4. doi: 10.1021/cc900130a.
PMID:19863100
Abstract
A one-pot, pseudo four-component method for the efficient and simple synthesis of spiro[diindeno[1,2-b:2',1'-e]pyridine-11,3'-indoline]-2',10,12-trione derivatives in refluxing acetonitrile is reported. The features of this procedure are mild reaction conditions, high yields of products, and operational simplicity.
摘要
报道了一种在回流乙腈中高效简便地合成螺[二茚并[1,2 - b:2',1'- e]吡啶 - 11,3'- 吲哚啉]-2',10,12 - 三酮衍生物的一锅法、伪四组分方法。该方法的特点是反应条件温和、产物收率高且操作简便。
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