McHugh Michelle K, Symanski Elaine, Pompeii Lisa A, Delclos George L
Division of Environmental and Occupational Health Sciences, University of Texas School of Public Health, Houston, Texas 77030, USA.
J Asthma. 2009 Oct;46(8):759-66. doi: 10.1080/02770900903067895.
The prevalence of asthma has increased over the last three decades with females exhibiting a higher prevalence of asthma than males. The objective of this study was to obtain gender-specific estimates of the prevalence of current and ever asthma and describe the relationships between risk factors and asthma by gender in US men and women ages 20 to 85.
Data for this study came from two cycles (2001-2002 and 2003-2004) of National Health and Nutrition Examination Survey (NHANES) and included 9,243 eligible adults: 4,589 females and 4,654 males. Multiple logistic regression was used to investigate gender-specific associations between race/ethnicity, body mass index (BMI), sociodemographic characteristics, and smoking habits for current asthma and ever asthma.
The prevalence of current asthma was 8.8% for women and 5.8% for men, while the prevalence of ever having been diagnosed with asthma was higher (13.7% and 10.4% for women and men, respectively). Current asthma was less prevalent in Mexican American women (1.9%) and men (0.9%) born in Mexico as compared to Mexican Americans born in the U.S. (8.7% and 5.2% for women and men, respectively) or for any other ethnic group. Approximately 20% of extremely obese women and men had ever been diagnosed with asthma; among this group, 15% reported they had current asthma. Results from multiple logistic regression models indicate that extreme obesity and living in poverty were strongly associated with current and ever asthma for both women and men, as was former smoking and ever asthma for men.
As compared to previous NHANES reports, our results indicate that the prevalence of asthma among U.S. adults continues to increase. Further, our findings of marked differences among subgroups of the population suggest asthma-related disparities for impoverished persons and greater prevalence of asthma among obese and extremely obese US adults.
在过去三十年中,哮喘的患病率有所上升,女性哮喘患病率高于男性。本研究的目的是获得美国20至85岁男性和女性当前及曾经患哮喘患病率的性别特异性估计值,并描述危险因素与哮喘之间按性别划分的关系。
本研究的数据来自两个周期(2001 - 2002年和2003 - 2004年)的国家健康和营养检查调查(NHANES),包括9243名符合条件的成年人:4589名女性和4654名男性。多元逻辑回归用于研究种族/民族、体重指数(BMI)、社会人口统计学特征和吸烟习惯与当前哮喘和曾经患哮喘之间的性别特异性关联。
女性当前哮喘患病率为8.8%,男性为5.8%,而曾经被诊断为哮喘的患病率更高(女性和男性分别为13.7%和10.4%)。与在美国出生的墨西哥裔美国人(女性和男性分别为8.7%和5.2%)或任何其他种族群体相比,出生在墨西哥的墨西哥裔美国女性(1.9%)和男性(0.9%)当前哮喘患病率较低。大约20%的极度肥胖女性和男性曾经被诊断为哮喘;在这一群体中,15%报告他们患有当前哮喘。多元逻辑回归模型的结果表明,极度肥胖和生活贫困与女性和男性的当前及曾经患哮喘密切相关,男性的既往吸烟与曾经患哮喘也密切相关。
与之前的NHANES报告相比,我们的结果表明美国成年人中哮喘的患病率持续上升。此外,我们在人群亚组中发现的显著差异表明,贫困人群存在与哮喘相关的差异,并且美国肥胖和极度肥胖成年人中哮喘患病率更高。