Department of Pediatrics, Ohio State University, Columbus, OH, USA.
Acta Paediatr. 2010 Feb;99(2):188-93. doi: 10.1111/j.1651-2227.2009.01563.x. Epub 2009 Oct 26.
To test the hypothesis that implementing guidelines for the standardized care of the extremely premature infant (<27 weeks) in the first week of life would improve patient outcomes in an all referral NICU.
Data were collected on all infants <27 weeks gestational age and <7 days of age on admission cared for using these small baby guidelines (SBG), as well as on all age-matched infants admitted the year prior (comparison).
Thirty-seven patients were cared for utilizing the SBG and 40 patients were in the comparison group. There were no differences between the groups in gestational age, birthweight or age on admission. There was no difference in survival to discharge (73% SBG, 70% comparison). The mean length of stay for survivors was 112 +/- 38 days SBG and 145 +/- 76 days (p < 0.05) comparison group. Survival without BPD was greater in the SBG group (24%) than in the comparison group (9%; p < 0.05), and survival without severe IVH was greater in the SBG group (65%) than in the comparison group (38%; p < 0.01).
These data demonstrate that applying a unified approach to the care of the extremely premature infant in the first week of life resulted in a decrease in the length of hospitalization and improved patient outcomes.
检验以下假设，即在极低体重新生儿（<27 周）生命的第一周实施标准化护理指南，是否会改善所有转诊新生儿重症监护病房（NICU）的患者预后。
我们收集了所有使用小婴儿护理指南（SBG）进行治疗的<27 周胎龄和<7 天入院的极低体重新生儿的数据，以及同年入院的所有年龄匹配的婴儿（对照）的数据。
有 37 名患者使用 SBG 进行治疗，40 名患者为对照组。两组在胎龄、出生体重或入院年龄方面均无差异。出院生存率无差异（SBG 组为 73%，对照组为 70%）。幸存者的平均住院时间为 SBG 组 112 +/- 38 天和对照组 145 +/- 76 天（p < 0.05）。SBG 组无 BPD 生存率（24%）高于对照组（9%；p < 0.05），SBG 组无严重 IVH 生存率（65%）高于对照组（38%；p < 0.01）。
这些数据表明，在生命的第一周对极低体重新生儿采用统一的护理方法可缩短住院时间，改善患者预后。
