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多学科质量改进努力以降低支气管肺发育不良的发生率。

A multidisciplinary quality improvement effort to reduce bronchopulmonary dysplasia incidence.

机构信息

Division of Neonatology, Nationwide Children's Hospital, Columbus, OH, USA.

Research Institute and Center for Perinatal Research, Nationwide Children's Hospital, Columbus, OH, USA.

出版信息

J Perinatol. 2020 Apr;40(4):681-687. doi: 10.1038/s41372-019-0574-8. Epub 2020 Jan 6.

DOI:10.1038/s41372-019-0574-8
PMID:31907398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7223819/
Abstract

BACKGROUND

Bronchopulmonary Dysplasia (BPD) is the most common prematurity complication. Although several practices have been proposed for BPD prevention, none of these in isolation prevent BPD.

METHODS

Our initiative focused on two key drivers: oxygen management and noninvasive ventilation strategies. We created best practice guidelines and followed outcome measures using Shewhart control charts.

RESULTS

PDSAs of protocols preceded a large-scale rollout of a "0.21 by 28" campaign in 2014 leading to a special cause reduction in the "any BPD" rate, and a decrease in severe BPD (from 57 to 29%). At the end of 2017, we reinvigorated the project, which led to dramatic decreases in the "any BPD" rate to 41% and the "severe BPD" rate to 21%.

CONCLUSIONS

A multidisciplinary QI initiative focused on process improvement geared towards the pathophysiological contributors of BPD has successfully reduced the rate of BPD in an all referral level IV NICU.

摘要

背景

支气管肺发育不良(BPD)是最常见的早产儿并发症。尽管已经提出了几种预防 BPD 的措施,但没有一种措施可以单独预防 BPD。

方法

我们的举措侧重于两个关键驱动因素:氧管理和无创通气策略。我们制定了最佳实践指南,并使用休哈特控制图跟踪结果。

结果

方案的计划前 PDCA 于 2014 年大规模推出了“0.21 by 28”活动,导致“任何 BPD”率的特殊原因减少,严重 BPD(从 57 例降至 29%)减少。2017 年底,我们重新启动了该项目,这导致“任何 BPD”率显著下降至 41%,“严重 BPD”率下降至 21%。

结论

一项针对 BPD 病理生理原因的多学科质量改进举措成功降低了一家四级转诊新生儿重症监护病房的 BPD 发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/e79589ad9bfa/41372_2019_574_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/bbc4e6c36b84/41372_2019_574_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/4c0cdd70415a/41372_2019_574_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/99aa5cdf188c/41372_2019_574_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/e79589ad9bfa/41372_2019_574_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/bbc4e6c36b84/41372_2019_574_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/4c0cdd70415a/41372_2019_574_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/99aa5cdf188c/41372_2019_574_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51ab/7223819/e79589ad9bfa/41372_2019_574_Fig4_HTML.jpg

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本文引用的文献

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Effect of cumulative oxygen exposure on respiratory symptoms during infancy among VLBW infants without bronchopulmonary dysplasia.累积吸氧暴露对无支气管肺发育不良极低出生体重儿婴儿期呼吸症状的影响。
Pediatr Pulmonol. 2010 Apr;45(4):371-9. doi: 10.1002/ppul.21199.
2
Implementation of a multidisciplinary guideline-driven approach to the care of the extremely premature infant improved hospital outcomes.实施多学科指南驱动的方法来照顾极早产儿可改善医院结局。
Acta Paediatr. 2010 Feb;99(2):188-93. doi: 10.1111/j.1651-2227.2009.01563.x. Epub 2009 Oct 26.
支气管肺发育不良的发生发展中的表观遗传修饰:综述。
Pediatr Res. 2024 Aug;96(3):632-642. doi: 10.1038/s41390-024-03167-7. Epub 2024 Apr 3.
4
Synergistic effects of achieving perinatal interventions on bronchopulmonary dysplasia in preterm infants.实现围产期干预对早产儿支气管肺发育不良的协同作用。
Eur J Pediatr. 2024 Apr;183(4):1711-1721. doi: 10.1007/s00431-023-05355-9. Epub 2024 Jan 17.
5
Respiratory support strategies in the prevention of bronchopulmonary dysplasia: A single center quality improvement initiative.预防支气管肺发育不良的呼吸支持策略:一项单中心质量改进计划。
Front Pediatr. 2022 Dec 12;10:1012655. doi: 10.3389/fped.2022.1012655. eCollection 2022.
6
Association of time of first corticosteroid treatment with bronchopulmonary dysplasia in preterm infants.首剂皮质类固醇治疗时间与早产儿支气管肺发育不良的关系。
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Jt Comm J Qual Patient Saf. 2021 Oct;47(10):654-662. doi: 10.1016/j.jcjq.2021.06.003. Epub 2021 Jun 18.