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表达在 HEp-2 细胞中局部粘附样模式的非典型肠致病性大肠杆菌菌株的粘附因子。

Adherence factors in atypical enteropathogenic Escherichia coli strains expressing the localized adherence-like pattern in HEp-2 cells.

机构信息

Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, Rua Botucatu, 862, 3 degrees andar, 04023-062, São Paulo, SP, Brazil.

出版信息

J Clin Microbiol. 2010 Jan;48(1):302-6. doi: 10.1128/JCM.01980-09. Epub 2009 Oct 28.

Abstract

Although atypical enteropathogenic Escherichia coli (aEPEC) strains are frequently implicated in childhood diarrhea in developing countries, not much is known about their adherence properties. The phenotypic and genotypic characterization of 29 aEPEC strains expressing the localized adherence-like pattern points toward the involvement of E. coli common pilus (ECP), intimins, and other known E. coli adhesins in this pattern.

摘要

虽然非典型肠致病性大肠杆菌(aEPEC)菌株常与发展中国家儿童腹泻有关,但对其黏附特性知之甚少。29 株表达局灶黏附样模式的 aEPEC 菌株的表型和基因型特征表明,大肠杆菌普通菌毛(ECP)、内毒素和其他已知的大肠杆菌黏附素参与了这种模式。

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