Department of Respiratory Disease, CHU Arnaud de Villeneuve, Montpellier, France.
Thorax. 2009 Nov;64(11):999-1004. doi: 10.1136/thx.2008.112862.
The relationship between allergic rhinitis and asthma is now established, and most of the clinical, epidemiological and biological data recommend integrated management. Epithelial cells represent the first barrier of the upper and lower respiratory tracts and thus are logical targets for a comprehensive integrated therapeutic approach. This review discusses rhinosinusitis as a co-morbid condition, a precipitating or triggering condition, and an epiphenomenon as an integrated part of the disease. A better understanding and a more pragmatic method of diagnosis and management is needed using cost-effective long-term strategies.
变应性鼻炎与哮喘之间的关系现已确立，大多数临床、流行病学和生物学数据均推荐采用综合管理。上皮细胞是上、下呼吸道的第一道屏障，因此，它们是综合治疗方法的合理靶点。本文探讨了鼻-鼻窦炎作为一种共病、诱发或触发因素以及作为疾病的一种伴随现象的情况。需要采用具有成本效益的长期策略，以更好地理解和采用更务实的诊断和管理方法。
