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变应性鼻炎

Allergic rhinitis.

作者信息

Rosenfield Lana, Keith Paul K, Quirt Jaclyn, Small Peter, Ellis Anne K

机构信息

Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.

Division of Clinical Immunology and Allergy, Department of Medicine, McMaster University, Hamilton, ON, Canada.

出版信息

Allergy Asthma Clin Immunol. 2024 Dec 27;20(Suppl 3):74. doi: 10.1186/s13223-024-00923-6.

DOI:10.1186/s13223-024-00923-6
PMID:39731198
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11681636/
Abstract

Allergic rhinitis (AR) is a common disorder that is strongly linked to asthma and conjunctivitis. Classic symptoms include nasal congestion, nasal itch, rhinorrhea and sneezing. A thorough history, physical examination and assessment of allergen sensitization are important for establishing the diagnosis of AR. Intranasal corticosteroids and second-generation antihistamines are the mainstay of treatment. Allergen immunotherapy is an effective immune-modulating treatment for use in addition to or as an alternative to pharmacologic therapy. This article provides an overview on the pathophysiology, diagnosis, and appropriate management of AR.

摘要

变应性鼻炎(AR)是一种常见疾病,与哮喘和结膜炎密切相关。典型症状包括鼻塞、鼻痒、流涕和打喷嚏。详尽的病史、体格检查以及变应原致敏评估对于AR的诊断至关重要。鼻用糖皮质激素和第二代抗组胺药是主要治疗药物。变应原免疫疗法是一种有效的免疫调节治疗方法,可作为药物治疗的辅助手段或替代方案。本文概述了AR的病理生理学、诊断及合理管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbd/11681636/e8a2c5695b7a/13223_2024_923_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbd/11681636/7aabef717259/13223_2024_923_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbd/11681636/e8a2c5695b7a/13223_2024_923_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbd/11681636/7aabef717259/13223_2024_923_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfbd/11681636/e8a2c5695b7a/13223_2024_923_Fig2_HTML.jpg

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本文引用的文献

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Focused allergic rhinitis practice parameter for Canada.加拿大变应性鼻炎针对性诊疗规范
Allergy Asthma Clin Immunol. 2024 Aug 8;20(1):45. doi: 10.1186/s13223-024-00899-3.
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Relative Humidity and Its Impact on the Immune System and Infections.相对湿度及其对免疫系统和感染的影响。
Int J Mol Sci. 2023 May 29;24(11):9456. doi: 10.3390/ijms24119456.
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Allergen immunotherapy: past, present and future.变应原免疫治疗:过去、现在和未来。
Allergy Asthma Clin Immunol. 2025 Feb 10;20(Suppl 3):81. doi: 10.1186/s13223-025-00949-4.
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Long-term efficacy of the sublingual and subcutaneous routes in allergen immunotherapy.舌下和皮下途径在变应原免疫治疗中的长期疗效。
Allergy Asthma Proc. 2022 Jul 1;43(4):292-298. doi: 10.2500/aap.2022.43.220026.
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Perception and control of allergic rhinitis in primary care.基层医疗中变应性鼻炎的认知与控制。
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Rhinitis 2020: A practice parameter update.变应性鼻炎 2020:实践参数更新。
J Allergy Clin Immunol. 2020 Oct;146(4):721-767. doi: 10.1016/j.jaci.2020.07.007. Epub 2020 Jul 22.
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Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence.基于推荐评估、制定与评价(GRADE)分级和真实世界证据的新一代变应性鼻炎及其对哮喘(ARIA)指南:变应性鼻炎。
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