Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
Org Biomol Chem. 2009 Nov 21;7(22):4590-3. doi: 10.1039/b915723a. Epub 2009 Sep 21.
Exposure to methylmercury causes severe damage to various tissues and organs in humans. Although a variety of fluorescent chemosensors have been exploited, only few biological monitoring systems for organomercury species have been described to date. In this report, we describe an irreversible rhodamine chemosensor for the detection of methylmercury and real-time monitoring of methylmercury in living cells and organisms.
甲基汞暴露会对人类的各种组织和器官造成严重损害。尽管已经开发出了多种荧光化学传感器,但迄今为止,只有少数用于有机汞物种的生物监测系统得到了描述。在本报告中,我们描述了一种用于检测甲基汞和实时监测活细胞和生物体中甲基汞的不可逆罗丹明化学传感器。