啮齿动物和人类嗜酸性粒细胞颗粒的结构。
The structure of eosinophil leukocyte granules in rodents and in man.
机构信息
Pathologisches Institut der Universität München, Germany, the Sloan-Kettering Institute for Cancer Research, New York, and The Rockefeller University, New York.
出版信息
J Cell Biol. 1966 Nov 1;31(2):349-62. doi: 10.1083/jcb.31.2.349.
Abstract
The structure of the specific granules of eosinophil leukocytes has been studied by electron microscopy in sections of tissues, buffy coats, and sediments of peritoneal washings of rats, mice, guinea pigs, and men. The core of eosinophil granules is a crystal which has a cubic lattice with a repeat of approximately 30 A in rodents and approximately 40 A in man. The chemical composition of the core is discussed in connection with recent cell fractionation studies, and the hypothesis that the core is a crystal of peroxidase is considered.
摘要
嗜酸性粒细胞的特殊颗粒的结构已通过电子显微镜在大鼠、小鼠、豚鼠和人的组织切片、血涂片和腹腔洗液沉淀物中进行了研究。嗜酸性粒细胞颗粒的核心是一个晶体，在啮齿动物中具有大约 30Å 的立方晶格重复，在人类中大约为 40Å。核心的化学成分与最近的细胞分级分离研究有关，并考虑了核心是过氧化物酶晶体的假设。
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