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动脉的潜伏生命。

LATENT LIFE OF ARTERIES.

机构信息

Laboratories of the Rockefeller Institute for Medical Research, New York.

出版信息

J Exp Med. 1910 Jul 23;12(4):460-86. doi: 10.1084/jem.12.4.460.

DOI:10.1084/jem.12.4.460
PMID:19867337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2124808/
Abstract

When a segment of artery, killed by heat, formalin or glycerin is transplanted, it undergoes a rapid degeneration. Its muscle fibers disappear while the tissue of the host reacts by building a new wall of connective tissue. When the transplanted vessel has been preserved in a condition of latent life, no degeneration of the wall occurs, or the wall undergoes only partial degeneration. The muscle fibers can keep their normal appearance, even for a long time after the operation. It is, therefore, demonstrated that arteries can be preserved outside of the body in a condition of unmanifested actual life. The best method of preservation consists of placing the vessels, immersed in vaselin, in an ice box, the temperature of which is slightly above the freezing point. From a surgical standpoint, the transplantation of preserved vessels can be used with some safety. When the arteries were kept in defibrinated blood or vaselin and in cold storage, the proportion of positive results was 75 and 80 per cent., and this can probably be increased.

摘要

当一段动脉因受热、甲醛或甘油而死亡并被移植时,它会迅速退化。其肌肉纤维消失,而宿主组织则通过构建新的结缔组织壁来反应。当移植的血管保存在潜在生命状态下时,不会发生壁的退化,或者壁仅发生部分退化。肌肉纤维可以保持正常外观,即使在手术后很长时间也是如此。因此,证明了动脉可以在体外保持未表现出的实际生命状态。最佳的保存方法是将浸泡在凡士林中的血管置于冰盒中,冰盒的温度略高于冰点。从外科角度来看,保存血管的移植可以安全使用。当将动脉保存在去纤维血或凡士林和冷藏中时,阳性结果的比例为 75%和 80%,这可能会增加。

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引用本文的文献

1
The use of free vascular transplants for bridging arterial defects; an historical review with particular reference to histological observations.游离血管移植用于桥接动脉缺损;特别参考组织学观察的历史回顾
Yale J Biol Med. 1950 Jan;22(3):273-90.