Department of Pathology of the Army Medical School, Washington.
J Exp Med. 1914 Apr 1;19(4):362-71. doi: 10.1084/jem.19.4.362.
A strain of Spirochoeta pallida isolated from the nervous system has shown the following constant characters: (1) thick form; (2) the production of hard, well demarcated lesions with necrotic centers; (3) a characteristic location of the lesion; (4) a short incubation period; (5) a tendency to generalize with lesions of the skin and eye, following local inoculation of the testicle and scrotum. It is suggested that these characters constitute a definite strain of highly invasive power and that a classification of members of the pallida group may be made in accordance with this power.
(1)厚壁形态;(2)产生坚硬、界限分明的病变,伴有坏死中心;(3)病变的特征位置;(4)潜伏期短;(5)局部接种睾丸和阴囊后,皮肤和眼部病变具有广泛扩散的趋势。这表明这些特征构成了一种具有高度侵袭力的确定菌株,并且可以根据这种能力对苍白密螺旋体组的成员进行分类。