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从神经系统分离出一株苍白密螺旋体的观察。

OBSERVATIONS ON A STRAIN OF SPIROCHAETA PALLIDA ISOLATED FROM THE NERVOUS SYSTEM.

机构信息

Department of Pathology of the Army Medical School, Washington.

出版信息

J Exp Med. 1914 Apr 1;19(4):362-71. doi: 10.1084/jem.19.4.362.

DOI:10.1084/jem.19.4.362
PMID:19867775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2125174/
Abstract

A strain of Spirochoeta pallida isolated from the nervous system has shown the following constant characters: (1) thick form; (2) the production of hard, well demarcated lesions with necrotic centers; (3) a characteristic location of the lesion; (4) a short incubation period; (5) a tendency to generalize with lesions of the skin and eye, following local inoculation of the testicle and scrotum. It is suggested that these characters constitute a definite strain of highly invasive power and that a classification of members of the pallida group may be made in accordance with this power.

摘要

从神经系统中分离出的一株苍白密螺旋体具有以下恒定特征

（1）厚壁形态；（2）产生坚硬、界限分明的病变，伴有坏死中心；（3）病变的特征位置；（4）潜伏期短；（5）局部接种睾丸和阴囊后，皮肤和眼部病变具有广泛扩散的趋势。这表明这些特征构成了一种具有高度侵袭力的确定菌株，并且可以根据这种能力对苍白密螺旋体组的成员进行分类。

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本文引用的文献

1
MORPHOLOGICAL AND PATHOGENIC VARIATIONS IN TREPONEMA PALLIDUM.苍白密螺旋体的形态学和病理学变异。
J Exp Med. 1912 Feb 1;15(2):201-4. doi: 10.1084/jem.15.2.201.