免疫血清中生长引起的肺炎球菌变异。
VARIATIONS IN THE PNEUMOCOCCUS INDUCED BY GROWTH IN IMMUNE SERUM.
机构信息
Hospital of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1916 Jul 1;24(1):49-68. doi: 10.1084/jem.24.1.49.
Abstract
- The growth of virulent pneumococci in homologous immune serum produces (a) variations in agglutinability, (b) decrease in virulence, (c) inhibition of capsule formation, (d) increase in phagocytability with normal serum, and (e) change in absorption power and antigenic properties. 2. Reversion to the original type in these changed forms takes place upon animal passage.
摘要
毒力肺炎球菌在同源免疫血清中的生长会导致（a）凝集能力的变化，（b）毒力的降低，（c）荚膜形成的抑制，（d）正常血清吞噬能力的增加，以及（e）吸收能力和抗原特性的改变。
在这些改变的形式中，通过动物传代会发生向原始类型的回复。
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