Pathological Laboratory of the Presbyterian Hospital, Columbia University, New York.
J Exp Med. 1916 Dec 1;24(6):683-8. doi: 10.1084/jem.24.6.683.
The comparative resistance of bacteria and human tissue cells to antiseptics and other chemicals may be easily tested by tissue cultures under conditions which approximate those found in the living body. A comparative study shows that while human cells (connective tissue and wandering cells) are highly resistant to many antiseptics, they are in general more easily killed than bacteria (Staphylococcus aureus). Of the antiseptics tested, which include mercuric chloride, iodine, potassium mercuric iodide, phenol, tricresol, hydrogen peroxide, hypochlorites (Dakin's solution), argyrol, and alcohol, the one which approaches most closely the ideal disinfectant is iodine, which kills bacteria in strengths that do not seriously injure connective tissue cells or wandering cells.
细菌和人体组织细胞对防腐剂和其他化学物质的相对抗性可以通过组织培养在接近体内条件下进行轻松测试。一项比较研究表明,虽然人体细胞(结缔组织和游走细胞)对许多防腐剂具有高度抗性,但它们通常比细菌(金黄色葡萄球菌)更容易被杀死。在所测试的防腐剂中,包括氯化汞、碘、碘化汞钾、苯酚、三甲酚、过氧化氢、次氯酸盐(达金溶液)、硝酸银和酒精,最接近理想消毒剂的是碘,它在不会严重伤害结缔组织细胞或游走细胞的强度下杀死细菌。