Tulandi T, Guralnick M
Department of Obstetrics and Gynecology, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada.
Fertil Steril. 1991 Jan;55(1):53-5. doi: 10.1016/s0015-0282(16)54058-8.
Thirty-four women with unruptured tubal ectopic pregnancy (EP) were randomly assigned to undergo salpingotomy without tubal suturing (n = 15) or salpingotomy with tubal suturing (n = 19). The reproductive performance of these patients was compared with 24 patients who underwent salpingectomy for their EP (historical control). Using life table analysis, the cumulative probability of intrauterine pregnancy (IUP) at 12 and 24 months was 45% and 45% after salpingotomy without tubal suturing and 21% and 47% after salpingotomy with tubal suturing, respectively. The cumulative probability of IUP after salpingectomy (21% and 26% at 12 and 24 months, respectively) was significantly lower than after salpingotomy with or without tubal suturing. There was no difference in the cumulative probability of EP after salpingotomy with or without tubal suturing, but it was significantly higher than after salpingectomy. In 18 women who subsequently underwent laparoscopy or laparotomy, no significant difference was found between the degree of adhesions after salpingotomy with or without tubal suturing. These findings suggest that IUP after conservative treatment is higher than after salpingectomy, but recurrent EP is also higher. Intrauterine pregnancy occurs earlier after salpingotomy without tubal suturing than after salpingotomy with tubal suturing. This might be because of rapid return of tubal function after healing by secondary intention.
34例未破裂输卵管异位妊娠(EP)患者被随机分为两组,分别接受不进行输卵管缝合的输卵管切开术(n = 15)或进行输卵管缝合的输卵管切开术(n = 19)。将这些患者的生殖表现与24例因EP接受输卵管切除术的患者(历史对照)进行比较。采用生命表分析,不进行输卵管缝合的输卵管切开术后12个月和24个月宫内妊娠(IUP)的累积概率分别为45%和45%,进行输卵管缝合的输卵管切开术后分别为21%和47%。输卵管切除术后IUP的累积概率(12个月和24个月分别为21%和26%)显著低于进行或未进行输卵管缝合的输卵管切开术后。进行或未进行输卵管缝合的输卵管切开术后EP的累积概率没有差异,但显著高于输卵管切除术后。在随后接受腹腔镜检查或剖腹手术的18例女性中,进行或未进行输卵管缝合的输卵管切开术后粘连程度没有显著差异。这些发现表明,保守治疗后的IUP高于输卵管切除术后,但复发性EP也更高。不进行输卵管缝合的输卵管切开术后宫内妊娠比进行输卵管缝合的输卵管切开术后更早发生。这可能是因为二期愈合后输卵管功能迅速恢复。