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腹腔镜输卵管切除术或输卵管切开术治疗输卵管妊娠的生育结局:95 例回顾性队列研究。

Fertility outcomes after laparoscopic salpingectomy or salpingotomy for tubal ectopic pregnancy: A retrospective cohort study of 95 patients.

机构信息

Departments of Gynecology, Zhejiang Provincial People's Hospital, No. 158 Shangtang Rd, Hangzhou, 310014, China.

Departments of Gynecology, Zhejiang Provincial People's Hospital, No. 158 Shangtang Rd, Hangzhou, 310014, China.

出版信息

Int J Surg. 2017 Dec;48:59-63. doi: 10.1016/j.ijsu.2017.09.058. Epub 2017 Sep 22.

Abstract

OBJECTIVE

This study presents our experience with laparoscopic surgery for tubal ectopic pregnancy (EP), sums up the different features of two commonly utilized laparoscopic surgeries, and compares subsequent post-salpingectomy or -salpingotomy reproductive outcomes in women with tubal EPs.

STUDY DESIGN

Medical history data of 95 patients diagnosed with tubal EP between January 2013 and December 2014 were analyzed in a retrospective, observational manner. All patients studied were offered two surgical management options: salpingectomy (removal of the entire fallopian tube), or salpingotomy (removal of products of gestation only, leaving the remainder of the tube intact). All 95 cases included in the study desired to preserve future fertility, and were followed up for 36 months after surgery. Follow-up data included evaluation for crude intrauterine pregnancy (IUP), recurrent EP and infertility.

RESULTS

Patients that underwent salpingectomy were noted to be significantly older than those that underwent salpingotomy (P < 0.05). In addition, childbearing rates were noted to be significantly higher in the salpingectomy group when compared to patients that underwent salpingotomy (P < 0.05). No significant differences were noted in mean dimension of mass, pregnancy rates, cesarean section rates and previous abortion rates between the two groups. We did not find a significant difference in fertility outcomes between the two groups.

CONCLUSIONS

Surgical management options for EP should be comprehensively evaluated in the clinical setting as numerous factors influence the decision making process. This paper provides a foundation for further studies upon which reliable surgical treatment guidelines for patients with tubal EP can be established.

摘要

目的

本研究介绍了我们在腹腔镜治疗输卵管妊娠(EP)方面的经验,总结了两种常用腹腔镜手术的不同特点,并比较了输卵管 EP 患者输卵管切除术后或切开术后的后续生殖结局。

研究设计

回顾性观察分析 2013 年 1 月至 2014 年 12 月期间诊断为输卵管 EP 的 95 例患者的病史资料。所有研究患者均提供了两种手术治疗选择:输卵管切除术(切除整个输卵管)或输卵管切开术(仅切除妊娠产物,保留输卵管其余部分完整)。所有纳入研究的 95 例患者均希望保留未来的生育能力,并在手术后随访 36 个月。随访数据包括评估粗宫内妊娠(IUP)、复发性 EP 和不孕。

结果

接受输卵管切除术的患者明显比接受输卵管切开术的患者年龄更大(P < 0.05)。此外,与接受输卵管切开术的患者相比,接受输卵管切除术的患者的生育率明显更高(P < 0.05)。两组间肿块的平均大小、妊娠率、剖宫产率和既往流产率无显著差异。两组间的生育结局无显著差异。

结论

应根据临床情况综合评估 EP 的手术治疗选择,因为许多因素会影响决策过程。本文为进一步研究提供了基础,为输卵管 EP 患者建立可靠的手术治疗指南。

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