The Henry Phipps Institute, University of Pennsylvania, Philadelphia.
J Exp Med. 1930 May 31;51(6):879-87. doi: 10.1084/jem.51.6.879.
Colloidal iron or ferric chloride injected into the inflamed peritoneal cavity is fixed in the cavity and fails to reach the retrosternal lymphatic nodes, whereas, in the absence of inflammation, iron accumulates in these nodes and becomes demonstrable by the Prussian blue reaction. Quantitative studies show that after intraperitoneal injection of ferric chloride the retrosternal lymphatic nodes of animals with normal peritoneal cavity contain approximately 56 per cent more iron than do the nodes of animals with inflamed peritoneal cavity. Ferric chloride injected into the circulating blood enters an inflamed area in the skin and the inflamed tissue gives the Prussian blue reaction. Quantitative determinations show that the amount of iron in inflamed areas is much greater than that found in inflamed areas of animals that have received no iron.
将胶体铁或氯化铁注入发炎的腹腔内会固定在该腔体内，无法到达胸骨后淋巴结，而在没有炎症的情况下，铁会积聚在这些淋巴结中，并通过普鲁士蓝反应显示出来。定量研究表明，在腹腔内注射氯化铁后，正常腹腔动物的胸骨后淋巴结中铁的含量比发炎腹腔动物的淋巴结高约 56%。注入循环血液的氯化铁进入皮肤的炎症区域，炎症组织呈现普鲁士蓝反应。定量测定表明，在已经接受过铁的动物的炎症区域中，铁的含量比在未接受铁的动物的炎症区域中的铁的含量大得多。
