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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Laboratory of General Pathology of The Royal University of Milan, Milan, Italy.

J Exp Med. 1931 Jan 1;53(1):1-9. doi: 10.1084/jem.53.1.1.

Congo red injected in vivo together with uric acid gives rise to more intense and diffuse red coloring in rats, especially in the subcutaneous and peri-articular tissues, than is the case in control rats injected simply with dye. 2. Uric add added in vitro to solutions of Congo red or trypan blue increases the speed of diffusion of these dyes, both through gelatin and the animal membranes (dialyzers). These results support a view long maintained by Professor Rondoni (25), namely, that some factor of an endothelial-capillary nature must be taken into consideration in manifestations of hyperuricemia and of gout.

刚果红与尿酸一起注入动物体内，会使大鼠，特别是皮下和关节周围组织的着色更加鲜明和弥散，比单纯注射染料的对照大鼠更明显。
尿酸加入刚果红或锥蓝的体外溶液中，增加了这些染料在明胶和动物膜（透析器）中的扩散速度。这些结果支持了朗托尼教授（25）长期以来的观点，即必须考虑内皮毛细血管性质的某种因素在高尿酸血症和痛风的表现中。

Laboratory of General Pathology of The Royal University of Milan, Milan, Italy.

J Exp Med. 1931 Jan 1;53(1):1-9. doi: 10.1084/jem.53.1.1.

Congo red injected in vivo together with uric acid gives rise to more intense and diffuse red coloring in rats, especially in the subcutaneous and peri-articular tissues, than is the case in control rats injected simply with dye. 2. Uric add added in vitro to solutions of Congo red or trypan blue increases the speed of diffusion of these dyes, both through gelatin and the animal membranes (dialyzers). These results support a view long maintained by Professor Rondoni (25), namely, that some factor of an endothelial-capillary nature must be taken into consideration in manifestations of hyperuricemia and of gout.

刚果红与尿酸一起注入动物体内，会使大鼠，特别是皮下和关节周围组织的着色更加鲜明和弥散，比单纯注射染料的对照大鼠更明显。
尿酸加入刚果红或锥蓝的体外溶液中，增加了这些染料在明胶和动物膜（透析器）中的扩散速度。这些结果支持了朗托尼教授（25）长期以来的观点，即必须考虑内皮毛细血管性质的某种因素在高尿酸血症和痛风的表现中。