Hospital of The Rockefeller Institute for Medical Research.
J Exp Med. 1930 Jun 30;52(1):73-9. doi: 10.1084/jem.52.1.73.
A comparison of the effect of stimulation upon the arterial subdivisions shows that these differ in irritability. The capillaries are most irritable, then come the small arterial branches, and last the main stems of arteries, these being the least irritable. The non-innervated blood vessels of the vascular membranes exhibit therefore the behavior described by G. Ricker in the case of those which have a nervous apparatus. We have demonstrated accordingly similar properties in vessels which are not innervated as in those which are. Certain differences exist however. The action of adrenalin on the vessels of the vascular membrane is inconstant and certain other substances are wholly ineffective. Ricker's experiments have advanced knowledge on the regularity of the vascular reactions and have paved the way for these experiments of ours. The result of our experiments with vessels free of nerves suggests that a reexamination may be fruitful of the mechanism which obtains in innervated vessels. There can be no doubt that nerves play a rôle in the behavior of vessels; it appears now to be necessary to define more accurately precisely what this is.
刺激对动脉分支的影响的比较表明,这些分支的兴奋性不同。毛细血管最敏感,其次是小动脉分支,最后是动脉主干,这些分支的兴奋性最低。因此,无神经支配的血管膜中的血管表现出与具有神经支配的血管所描述的行为相似。我们在没有神经支配的血管中也证明了类似的特性。然而,存在某些差异。肾上腺素对血管膜血管的作用是不稳定的,而某些其他物质则完全无效。里克尔的实验使人们对血管反应的规律性有了更多的了解,并为我们的这些实验铺平了道路。我们对无神经支配的血管进行实验的结果表明,对受神经支配的血管的机制进行重新检查可能会有成效。毫无疑问,神经在血管的行为中起作用;现在似乎有必要更准确地定义这是什么。