结核蛋白与多糖的毒性研究。
A STUDY OF THE TOXIC PROPERTIES OF TUBERCULO-PROTEINS AND POLYSACCHARIDES.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1931 Jan 1;53(1):51-80. doi: 10.1084/jem.53.1.51.
Abstract
The temperature reaction in tuberculous and normal guinea pigs and rabbits is elicited by the tuberculo-protein and probably not at all by the polysaccharides. The polysaccharides may have some killing power under certain conditions, but this is not as consistently related to dosage as in the case of the proteins. Both proteins and polysaccharides cause a change in the white blood cells when introduced by any route.
摘要
结核菌素蛋白可引起豚鼠和家兔的体温反应，而非多糖，可能在某些条件下多糖有一定的杀菌力，但与蛋白质不同，这种杀菌力与剂量的关系并不一致。无论通过何种途径引入，蛋白质和多糖都会引起白细胞的变化。
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