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关于肺炎球菌之间免疫学关系的研究：五、酵母Ⅱ型肺炎球菌抗原与抗血清之间的过敏反应和沉淀。

STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : V. ANAPHYLAXIS AND PRECIPITATION BETWEEN ANTIGENS AND ANTISERA OF YEAST OF TYPE II PNEUMOCOCCI.

机构信息

Department of Bacteriology and Immunology, Vanderbilt University Medical School, Nashville.

出版信息

J Exp Med. 1931 Mar 31;53(4):527-34. doi: 10.1084/jem.53.4.527.

DOI:10.1084/jem.53.4.527
PMID:19869862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2131976/
Abstract

This paper reports inter-reactions of anaphylaxis and precipitation between antigens and antisera derived from the Type II variety of pneumococcus and from one variety of yeast. That the reactions occurred only with Type II and not with Types I and III is proof that the pneumococcus antigen responsible for the anaphylaxis of the antiyeast sensitized animals was the type-specific carbohydrate (S). Pronounced differences in respect to reactivity with the pneumococcus antigen were found between individual antiyeast sera that were of equal potency in respect to reactivity with the yeast antigen. This fact emphasizes the desirability of the use of antisera from a large number of individual animals in the study of microbial inter-relationships.

摘要

本文报告了来自 II 型肺炎球菌和一种酵母的抗原和抗血清之间的过敏反应和沉淀的相互作用。只有 II 型而不是 I 型和 III 型发生反应，证明了引起抗酵母致敏动物过敏的肺炎球菌抗原是型特异性碳水化合物（S）。在与肺炎球菌抗原的反应性方面，个体抗酵母血清之间存在明显差异，而这些血清在与酵母抗原的反应性方面具有同等效力。这一事实强调了在研究微生物相互关系时使用大量个体动物的抗血清的必要性。

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本文引用的文献

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STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : IV. ACTIVE IMMUNIZATION OF MICE AGAINST TYPE II PNEUMOCOCCI BY VACCINATION WITH YEAST.关于肺炎球菌免疫关系的研究 IV. 通过酵母接种对 II 型肺炎球菌进行小鼠主动免疫
J Exp Med. 1929 Oct 31;50(5):579-81. doi: 10.1084/jem.50.5.579.
2
STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : III. RELATIONSHIP BETWEEN A VARIETY OF SACCHAROMYCES CEREVISIAE AND THE TYPE II VARIETY OF DIPLOCOCCUS PNEUMONIAE (PNEUMOCOCCUS).关于肺炎球菌免疫关系的研究：III. 各种酿酒酵母与 II 型肺炎双球菌（肺炎球菌）之间的关系。
J Exp Med. 1929 Jan 31;49(2):183-93. doi: 10.1084/jem.49.2.183.
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STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : II. A COMPARISON OF THE ANTIBODY RESPONSES OF MICE AND OF RABBITS TO IMMUNIZATION WITH TYPICAL TYPE III PNEUMOCOCCI AND TO IMMUNIZATION WITH A RELATED STRAIN.关于肺炎球菌免疫关系的研究：Ⅱ. 小鼠和兔对典型Ⅲ型肺炎球菌免疫和同源菌株免疫的抗体反应比较。
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