睾丸提取物对体外红细胞的影响。
THE EFFECT OF TESTICLE EXTRACT ON RED BLOOD CELLS IN VITRO.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1931 Jul 31;54(2):197-206. doi: 10.1084/jem.54.2.197.
Abstract
Testicle extract possesses a notable power to increase red cell fragility. Testicle extracts of the rat, rabbit and guinea pig all exhibit this property, which is most pronounced with the extract from the rat and least so with that from the guinea pig. Splenic extract does not possess the property, or possesses it only to a very slight degree. These results support the hypothesis that the factor in testicle extract which enhances infections (the Reynals factor) does so by altering the permeability of the host tissue.
摘要
睾丸提取物具有显著增加红细胞脆性的能力。大鼠、兔和豚鼠的睾丸提取物均表现出这种特性，其中大鼠提取物的作用最为明显，豚鼠提取物的作用则最弱。脾提取物没有这种特性，或者只有非常轻微的特性。这些结果支持了这样一种假设，即睾丸提取物中增强感染的因素（雷纳尔斯因子）是通过改变宿主组织的通透性来实现的。
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