关于存在于细菌中的某种扩散因子及其对细菌侵袭性的意义的研究。
STUDIES ON A CERTAIN SPREADING FACTOR EXISTING IN BACTERIA AND ITS SIGNIFICANCE FOR BACTERIAL INVASIVENESS.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1933 Jul 31;58(2):161-81. doi: 10.1084/jem.58.2.161.
Abstract
Invasive strains of staphylococcus and streptococcus contain a soluble factor which markedly increases tissue permeability and enhances the infections produced by these organisms, by other bacteria, and by vaccine virus as well. The non-invasive strains of the same species of staphylococci and streptococci do not contain this factor. The enhancing substance elaborated locally by organisms passes into the circulating blood and bringing about a general increase of tissue permeability may act to enhance local infections elsewhere. The factor is similar in the phenomena it elicits to the spreading factor extracted from many animal tissues, especially from testicle.
摘要
侵袭性葡萄球菌和链球菌含有一种可溶性因子，这种因子显著增加了组织通透性，并增强了这些生物体、其他细菌以及疫苗病毒引起的感染。同一物种的非侵袭性葡萄球菌和链球菌不含有这种因子。由生物体在局部产生的增强物质进入循环血液，并导致组织通透性普遍增加，可能会增强其他部位的局部感染。这种因子在引起的现象上与从许多动物组织中提取的扩散因子相似，特别是从睾丸中提取的扩散因子。
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3
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