睾丸提取物和正常血清对兔可移植上皮肿瘤的影响。
THE EFFECT OF TESTICLE EXTRACT AND OF NORMAL SERUM ON A TRANSPLANTABLE EPITHELIAL TUMOR OF THE RABBIT.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1931 Sep 30;54(4):493-8. doi: 10.1084/jem.54.4.493.
Abstract
Extract of rat, rabbit or bull testicle prevents or retards the growth of a rabbit tumor when a mixture of the extract and a tumor cell suspension is inoculated intradermally. Similar mixtures, made with normal rabbit serum instead of testicle extract, give rise to tumors which grow with unusual rapidity. The results are the opposite of those obtained with pathogenic bacteria or filtrable viruses which are enhanced by testicle extract and generally inhibited by normal serum.
摘要
从大鼠、兔子或公牛的睾丸中提取的物质，当与提取物和肿瘤细胞悬浮液的混合物皮内接种时，可以预防或延缓兔子肿瘤的生长。用正常兔血清代替睾丸提取物制成的类似混合物，会导致肿瘤异常迅速地生长。结果与致病性细菌或滤过性病毒相反，这些细菌或病毒被睾丸提取物增强，通常被正常血清抑制。
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