Falkner B, Kushner H
Department of Pediatrics, Hahnemann University, Philadelphia, Pa.
Hypertension. 1991 Jan;17(1 Suppl):I162-5. doi: 10.1161/01.hyp.17.1_suppl.i162.
The interaction of sodium sensitivity and stress-induced cardiovascular reactivity was studied in white and black young adults aged 18-23 years. The cardiovascular response to difficult mental arithmetic was measured before and after 14 days of oral sodium loading (10 g NaCl/day added to the usual diet). A sodium-sensitive blood pressure response occurred in 18.4% of whites and 37.3% of blacks. A significant correlation between blood pressure change and sodium excretion occurred in the sodium-sensitive group (r = - 0.28, p less than 0.01). High sodium intake did not augment blood pressure or heart rate response to the beta-adrenergic-mediated stimulus of mental arithmetic in the population, which was grouped by blood pressure, race, or sodium sensitivity.
在18至23岁的白人和黑人青年成年人中研究了钠敏感性与应激诱导的心血管反应性之间的相互作用。在口服钠负荷（每天10克氯化钠添加到日常饮食中）14天前后，测量了对困难心算的心血管反应。18.4%的白人及37.3%的黑人出现了钠敏感性血压反应。在钠敏感组中，血压变化与钠排泄之间存在显著相关性（r = -0.28，p < 0.01）。在按血压、种族或钠敏感性分组的人群中，高钠摄入并未增强对心算的β-肾上腺素能介导刺激的血压或心率反应。
