口服型 I、II、III 型肺炎球菌可溶性特异性物质的命运。
THE FATE OF ORALLY ADMINISTERED SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS TYPES I, II AND III.
机构信息
Department of Biological Chemistry, College of Physicians and Surgeons, Columbia University, and the Bureau of Laboratories, Department of Health of the City of New York, New York.
出版信息
J Exp Med. 1932 Jan 1;55(1):13-25. doi: 10.1084/jem.55.1.13.
Abstract
- Rats, when fed the soluble specific substance of Types I, II and III pneumococcus, excrete a very large proportion in the feces. 2. Following ingestion of these substances, tests sensitive enough to detect 1 part in 2,000,000 of serum, and 1 part in 3,000,000 of urine, were negative. 3. The polysaccharide of Type I, when recovered from the feces, is as active an immunizing agent as it was originally.
摘要
给老鼠喂食 I、II 和 III 型肺炎球菌的可溶性特异性物质时，很大一部分会从粪便中排出。
这些物质被摄入后，检测血清中 1/2000000 和尿液中 1/3000000 的敏感度足以呈阴性。
从粪便中回收的 I 型多糖，其免疫原性与最初一样强。
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THE ROLE OF THE SOLUBLE SPECIFIC SUBSTANCE IN ORAL IMMUNIZATION AGAINST PNEUMOCOCCUS TYPES II AND III.可溶性特异物质在 II 型和 III 型肺炎球菌口服免疫中的作用。
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本文引用的文献
1
THE ROLE OF THE SOLUBLE SPECIFIC SUBSTANCE IN ORAL IMMUNIZATION AGAINST PNEUMOCOCCUS TYPES II AND III.可溶性特异物质在 II 型和 III 型肺炎球菌口服免疫中的作用。
J Exp Med. 1932 Jan 1;55(1):1-12. doi: 10.1084/jem.55.1.1.
2
THE ROLE OF THE SOLUBLE SPECIFIC SUBSTANCE IN ORAL IMMUNIZATION AGAINST PNEUMOCOCCUS TYPE I.针对 I 型肺炎球菌的口服免疫中可溶性特异物质的作用。
J Exp Med. 1931 Nov 30;54(6):899-923. doi: 10.1084/jem.54.6.899.
3
STUDIES ON PNEUMOCOCCUS GROWTH INHIBITION : VI. THE SPECIFIC EFFECT OF PNEUMOCOCCUS SOLUBLE SUBSTANCE ON THE GROWTH OF PNEUMOCOCCI IN NORMAL SERUM-LEUCOCYTE MIXTURES.肺炎球菌生长抑制的研究：六、肺炎球菌可溶性物质对正常血清-白细胞混合物中肺炎球菌生长的特异性影响。
J Exp Med. 1926 Apr 30;43(5):633-45. doi: 10.1084/jem.43.5.633.
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