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PROTECTION OF ADRENALECTOMIZED ANIMALS AGAINST BACTERIAL INTOXICATION BY AN EXTRACT OF THE ADRENAL CORTEX.用肾上腺皮质提取物保护肾上腺切除动物免受细菌中毒。
J Exp Med. 1932 Jan 1;55(1):63-9. doi: 10.1084/jem.55.1.63.
2
THE INFLUENCE OF THE ADRENAL GLANDS ON RESISTANCE : II. THE TOXIC EFFECT OF KILLED BACTERIA IN ADRENALECTOMIZED RATS.肾上腺对抵抗力的影响：Ⅱ. 肾上腺切除大鼠中死亡细菌的毒性作用。
J Exp Med. 1924 Feb 29;39(3):457-71. doi: 10.1084/jem.39.3.457.
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The use of adrenal cortical extract in cases of acute alcoholic intoxication.肾上腺皮质提取物在急性酒精中毒病例中的应用。
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[Protection of adrenalectomized rats against histamine intoxication with adrenal hormones and antihistaminics].[肾上腺切除大鼠用肾上腺激素和抗组胺药预防组胺中毒]
Rev Soc Argent Biol. 1953 Apr-May;29(1-2):2-9.
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Adrenal and urinary catecholamines during and after severe ethanol intoxication in rats: a profile of changes.大鼠严重乙醇中毒期间及之后肾上腺和尿儿茶酚胺：变化概况
Pharmacol Biochem Behav. 1984 Jul;21(1):125-31. doi: 10.1016/0091-3057(84)90141-2.
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Adrenal regeneration in the rat is mediated by mitogenic N-terminal pro-opiomelanocortin peptides generated by changes in precursor processing in the anterior pituitary.大鼠肾上腺再生是由垂体前叶前体加工变化产生的有丝分裂原性N端阿片促黑激素原肽介导的。
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The resistance of non-adrenalectomized rats to diphtheria toxin with and without adrenal cortical hormone treatment.未切除肾上腺的大鼠在接受和未接受肾上腺皮质激素治疗时对白喉毒素的抵抗力。
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[The distribution of water and electrolytes in the organism of normal and adrenalectomized, untreated and adrenal cortex hormone-treated rats and the influence of administration of large amounts of water].[正常及肾上腺切除、未治疗及肾上腺皮质激素治疗大鼠机体中水和电解质的分布以及大量饮水的影响]
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The effect of DOCA and of adrenal cortical extract on hepatic regeneration in adrenalectomized rats.去氧皮质酮（DOCA）和肾上腺皮质提取物对肾上腺切除大鼠肝脏再生的影响。
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Comparative value of corticosterone, hydrocortisone and adrenal cortex extract given by continuous intravenous injection in sustaining the ability of adrenalectomized rat to work.持续静脉注射皮质酮、氢化可的松和肾上腺皮质提取物在维持肾上腺切除大鼠工作能力方面的比较价值。
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Review article: Early steroid administration for traumatic haemorrhagic shock: A systematic review.综述文章：创伤性失血性休克早期类固醇治疗：系统评价。
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本文引用的文献

1
On Diminished Resistance Following Suprarenalectomy in the Rat and the Protection Afforded by Autoplastic Transplants.大鼠肾上腺切除术后抵抗力降低及自体移植提供的保护
Am J Pathol. 1926 Sep;2(5):421-30.
2
THE INFLUENCE OF THE ADRENAL GLANDS ON RESISTANCE : II. THE TOXIC EFFECT OF KILLED BACTERIA IN ADRENALECTOMIZED RATS.肾上腺对抵抗力的影响：Ⅱ. 肾上腺切除大鼠中死亡细菌的毒性作用。
J Exp Med. 1924 Feb 29;39(3):457-71. doi: 10.1084/jem.39.3.457.

用肾上腺皮质提取物保护肾上腺切除动物免受细菌中毒。

PROTECTION OF ADRENALECTOMIZED ANIMALS AGAINST BACTERIAL INTOXICATION BY AN EXTRACT OF THE ADRENAL CORTEX.

机构信息

Department of Physiology, the University of Buffalo, Buffalo, and the Department of Surgery, the University of Rochester, School of Medicine and Dentistry, Rochester, N. Y.

出版信息

J Exp Med. 1932 Jan 1;55(1):63-9. doi: 10.1084/jem.55.1.63.

DOI:10.1084/jem.55.1.63
PMID:19869979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2132066/
Abstract
  1. The resistance of adrenal-deficient rats to bacterial intoxication has been significantly increased by an extract of the adrenal cortex. 2. This is shown both for acute intoxication with killed Bacillus typhosus and for chronic intoxication with killed Staphylococcus aureus. 3. During the height of the bacterial intoxication relatively large amounts of the cortical hormone are apparently required to maintain the animals. 4. It is considered probable that a human pyogenic infection imposes a severe load upon the adrenal cortex.
摘要

  1. 肾上腺皮质提取物可显著提高肾上腺功能不全大鼠对细菌中毒的抵抗力。

  2. 这在急性伤寒杆菌致死性中毒和慢性金黄色葡萄球菌致死性中毒中均有表现。

  3. 在细菌中毒的高峰期，显然需要相对大量的皮质激素来维持动物的生命。

  4. 人们认为，化脓性感染会给肾上腺皮质带来严重的负担。