Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
J Exp Med. 1936 Mar 31;63(4):533-46. doi: 10.1084/jem.63.4.533.
A filtrable virus, identical with that which causes acute lymphocytic choriomeningitis, has been found to cause a disease in white mice. Naturally infected mice usually show no symptoms, but such animals inoculated intracerebrally with sterile bouillon or other materials develop characteristic symptoms. The same symptoms are produced by intracerebral injection of the virus into mice from a disease-free stock. Guinea pigs are very susceptible and are therefore useful for detecting the virus and for neutralization tests. The disease in both naturally infected and inoculated animals is discussed and the pathological findings given.
已发现一种可滤过的病毒，该病毒与引起急性淋巴细胞性脉络丛脑膜炎的病毒相同，可引起小白鼠发病。自然感染的小鼠通常无症状，但用无菌肉汤或其他物质脑内接种的动物则出现特征性症状。将病毒脑内接种于来自无病畜群的小鼠，也可产生同样的症状。豚鼠很易感，因此可用于检出病毒和进行中和试验。文中讨论了自然感染和接种动物的疾病，并给出了病理学发现。
