豚鼠的主动免疫接种马传染性脑脊髓炎病毒：Ⅱ.甲醛化病毒免疫接种。
ACTIVE IMMUNIZATION OF GUINEA PIGS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. IMMUNIZATION WITH FORMOLIZED VIRUS.
机构信息
Laboratories of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1936 Apr 30;63(5):745-65. doi: 10.1084/jem.63.5.745.
Abstract
From a study by quantitative methods, the conclusion is reached that a resistance of high degree may be induced in guinea pigs and mice against experimental equine encephalomyelitis by means of formolized vaccines in which no active virus can be demonstrated. The induced resistance is not due to residual traces of active virus which might possibly have escaped detection in the formolized tissue preparations.
摘要
从定量研究的结果得出结论，用福尔马林处理过的疫苗能使豚鼠和小白鼠对实验性马脑炎产生高度的抵抗力，而在这种疫苗中已不能检出有活力的病毒。这种诱导的抵抗力不是由于可能在福尔马林处理过的组织制剂中漏检的残余的有活力的病毒所致。
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