糖蛋白偶联物的化学免疫研究：十一、含葡萄糖醛酸和半乳糖醛酸的偶氮蛋白抗原的特异性。
CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : XI. THE SPECIFICITY OF AZOPROTEIN ANTIGENS CONTAINING GLUCURONIC AND GALACTURONIC ACIDS.
机构信息
Hospital of The Rockefeller Institute for Medical Research.
出版信息
J Exp Med. 1937 Jul 31;66(2):191-205. doi: 10.1084/jem.66.2.191.
Abstract
- Azoprotein antigens containing glucuronic and galacturonic acids give rise in rabbits to specific antibodies. The immune sera show no serological crossing with antigens containing glucose or galactose. 2. The galacturonic acid antigen reacts in antipneumococcus horse serum Type I in high dilutions. 3. Azoprotein antigens containing galacturonic acid, benzene sulfonic and carboxylic acids precipitate in antipneumococcus horse sera of various types but not in normal horse serum. The mechanism underlying these cross reactions is discussed.
摘要
含有葡萄糖醛酸和半乳糖醛酸的偶氮蛋白抗原在兔子体内产生特异性抗体。免疫血清与含葡萄糖或半乳糖的抗原无血清学交叉反应。
半乳糖醛酸抗原在抗肺炎球菌马血清 I 型中高稀释度反应。
含有半乳糖醛酸、苯磺酸和羧酸的偶氮蛋白抗原在各种类型的抗肺炎球菌马血清中沉淀，但在正常马血清中不沉淀。讨论了这些交叉反应的机制。
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