Hospital of The Rockefeller Institute for Medical Research.
J Exp Med. 1937 Sep 30;66(4):413-24. doi: 10.1084/jem.66.4.413.
The ability to carry out with some measure of precision mouse protection tests for the estimation of potency of antipneumococcus sera has made possible the correlation of the protective potency with the amount of specifically precipitable protein. With antipneumococcus rabbit sera these protective ratios are relatively constant and higher than those with immune horse serum. Type I antipneumococcus horse sera, on the other hand, show no such constancy but fall into two groups; and there is as yet no simple method for determining to which group a serum belongs.
进行一定精度的抗肺炎球菌血清效价估计的小鼠保护试验的能力,使得将保护效力与特异性沉淀蛋白的量相关联成为可能。用抗肺炎球菌兔血清,这些保护比相对恒定且高于用免疫马血清。另一方面,I 型抗肺炎球菌马血清则没有这种恒定性,而是分为两组;而且目前还没有一种简单的方法来确定一个血清属于哪一组。