Laboratories of the International Health Division of The Rockefeller Foundation, New York.
J Exp Med. 1940 Jun 30;72(1):69-77. doi: 10.1084/jem.72.1.69.
In a study of mouse encephalomyelitis the following observations were made:- 1. A definite relationship exists between the amount of virus inoculated intracerebrally and the length of the incubation period. 2. The reciprocal of the incubation period was found to be approximately proportionate to the logarithm of the amount of virus inoculated. The relationship can, therefore, be given a simple mathematical form. 3. This fact provides a basis for a new method for measurement of the activity of mouse encephalomyelitis virus.
在一项关于鼠脑脊髓炎的研究中,观察到以下结果:- 1. 脑内接种病毒的量与潜伏期的长短之间存在明确的关系。2. 潜伏期的倒数与接种病毒量的对数大致成比例。因此,该关系可以用简单的数学形式表示。3. 这一事实为测量鼠脑脊髓炎病毒活性提供了一种新的方法。