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流感病毒的中和作用:血清量与中和病毒量之间的线性关系。

NEUTRALIZATION OF EPIDEMIC INFLUENZA VIRUS : THE LINEAR RELATIONSHIP BETWEEN THE QUANTITY OF SERUM AND THE QUANTITY OF VIRUS NEUTRALIZED.

机构信息

Laboratories of the International Health Division of The Rockefeller Foundation, New York.

出版信息

J Exp Med. 1939 Jul 31;70(2):209-22. doi: 10.1084/jem.70.2.209.

Abstract

A linear relationship exists between the logarithm of the quantity of epidemic influenza virus neutralized and the logarithm of the quantity of antiserum which is capable of achieving this result. This relationship is the same for the serum of a ferret convalescent from experimental influenza as for the serum of a rabbit immunized with the virus. By means of the linear relationship between virus and antiserum it is possible to determine a fixed, rather than a relative, value for the neutralizing capacity of a serum.

摘要

在被中和的流行性感冒病毒数量的对数与能够达到这一结果的抗血清数量的对数之间存在线性关系。这种关系对于从实验性流感中康复的雪貂的血清和用病毒免疫的兔的血清是相同的。通过病毒和抗血清之间的线性关系,可以确定血清的中和能力的一个固定值,而不是一个相对值。

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