Department of Physiology, College of Physicians and Surgeons, Columbia University, New York, and The Marine Biological Laboratory, Woods Hole, Massachusetts.
J Gen Physiol. 1941 Mar 20;24(4):535-49. doi: 10.1085/jgp.24.4.535.
The change in the transverse impedance of the squid giant axon caused by direct current flow has been measured at frequencies from 1 kc. per second to 500 kc. per second. The impedance change is equivalent to an increase of membrane conductance at the cathode to a maximum value approximately the same as that obtained during activity and a decrease at the anode to a minimum not far from zero. There is no evidence of appreciable membrane capacity change in either case. It then follows that the membrane has the electrical characteristics of a rectifier. Interpreting the membrane conductance as a measure of ion permeability, this permeability is increased at the cathode and decreased at the anode.
已在 1 千赫到 500 千赫的频率范围内测量了由直流电引起的鱿鱼巨大轴突的横向阻抗变化。阻抗变化相当于阴极处膜电导的增加，最大值约与活动期间获得的电导相同，而阳极处的减小则接近零。在这两种情况下，都没有明显的膜电容变化的证据。因此，可以得出结论，膜具有整流器的电学特性。将膜电导解释为离子通透性的度量，阴极处的通透性增加，而阳极处的通透性降低。
