[威灵仙根茎中三萜皂苷的研究]
[Studies on triterpenoid saponins in the rhizome of Anemone flaccida].
作者信息
Han Lin-Tao, Huang Fang
机构信息
Key Laboratory of "Traditional Chinese Medicine Resource and Compound Prescription", Ministry of Education/Hubei College of TCM, Wuhan 430065, China.
出版信息
Zhong Yao Cai. 2009 Jul;32(7):1059-62.
OBJECTIVE
To study the triterpenoid saponins in the rhizome of Anemone flaccida.
METHODS
The constituents were separated with various chromatographic techniques and their structures were elucidated by means of physicochemical properties and the analysis of their spectral datas.
RESULTS
Five compounds were isolated and identified as 3-O-beta-D-glucuronypyranosyl-oleanolic acid-28-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl(1 --> 6)-beta-D-glucopyra noside (1), 3-O-beta-D-glucuronypyranosyl-oleanolic acid-28-O-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (2), 3-O-alpha-L-rhamnopyranosy (1 --> 2)-beta-D-glucopyranosyl-oleanolic acid-28-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (3), 3-O-alpha-L-rhamnopyranosyl (1 --> 2)-alpha-L-arabinopyrano-syl-oleanolic acid-28-O-alpha-L-rhamnopyranosyl (1 -->4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (4), 3-O-alpha-L-rhamnopyranosyl (1 --> 2)-beta-D-xylopyranosyl-oleanolic acid-28-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (5).
CONCLUSION
Compound 1 - 4 are isolated from this plant for the first time. Compound 1,2 are isolated from this genus for the first time.
目的
研究威灵仙根茎中的三萜皂苷。
方法
采用多种色谱技术分离其成分，并通过理化性质及光谱数据分析阐明其结构。
结果
分离鉴定出5个化合物，分别为3 - O - β - D - 葡萄糖醛酸吡喃糖基 - 齐墩果酸 - 28 - O - α - L - 鼠李糖吡喃糖基（1→4）- β - D - 葡萄糖吡喃糖基（1→6）- β - D - 葡萄糖吡喃糖苷（1）、3 - O - β - D - 葡萄糖醛酸吡喃糖基 - 齐墩果酸 - 28 - O - β - D - 葡萄糖吡喃糖基（1→6）- β - D - 葡萄糖吡喃糖苷（2）、3 - O - α - L - 鼠李糖吡喃糖基（1→2）- β - D - 葡萄糖吡喃糖基 - 齐墩果酸 - 28 - O - α - L - 鼠李糖吡喃糖基（1→4）- β - D - 葡萄糖吡喃糖基（1→6）- β - D - 葡萄糖吡喃糖苷（3）、3 - O - α - L - 鼠李糖吡喃糖基（1→2）- α - L - 阿拉伯糖吡喃糖基 - 齐墩果酸 - 28 - O - α - L - 鼠李糖吡喃糖基（1→4）- β - D - 葡萄糖吡喃糖基（1→6）- β - D - 葡萄糖吡喃糖苷（4）、3 - O - α - L - 鼠李糖吡喃糖基（1→2）- β - D - 木糖吡喃糖基 - 齐墩果酸 - 28 - O - α - L - 鼠李糖吡喃糖基（1→4）- β - D - 葡萄糖吡喃糖基（1→6）- β - D - 葡萄糖吡喃糖苷（5）。
结论
化合物1 - 4首次从该植物中分离得到。化合物1、2首次从该属植物中分离得到。
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