Hu Chang-Ying, Xu De-Ping, Wu Yu-Mei, Ou Shi-Yi
Department of Food Science and Engineering, Jinan University, Guangzhou, China.
J Asian Nat Prod Res. 2010 Sep;12(9):801-8. doi: 10.1080/10286020.2010.505562.
Three new triterpenoid saponins, polygonoides C (1), D (2), and E (3), were obtained from the ethanolic extract of the rhizome of Polygonatum sibiricum Redoute. On the basis of NMR and ESI-MS spectra, and chemical evidence, the structures of the three new compounds were elucidated as 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-3β,7β,22β-trihydroxy-oleanolic acid (1), 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-3β,7β,22β-trihydroxy-oleanolic acid methyl ester (2), and 3-O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→4)-[α-L-rhamno-pyranosyl-(1→2)]-β-D-glucopyranosyl-3β,21β-dihydroxy-oleanolic acid 28-O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→3)-β-D-glucopyranoside (3).
从玉竹根茎的乙醇提取物中获得了三种新的三萜皂苷，即黄精皂苷C（1）、D（2）和E（3）。基于核磁共振波谱和电喷雾电离质谱，以及化学证据，确定了这三种新化合物的结构分别为3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃葡萄糖基-3β,7β,22β-三羟基齐墩果酸（1）、3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃葡萄糖基-3β,7β,22β-三羟基齐墩果酸甲酯（2）和3-O-β-D-吡喃葡萄糖基-(1→3)-β-D-吡喃葡萄糖基-(1→4)-[α-L-鼠李吡喃糖基-(1→2)]-β-D-吡喃葡萄糖基-3β,21β-二羟基齐墩果酸28-O-β-D-吡喃葡萄糖基-(1→3)-β-D-吡喃葡萄糖基-(1→3)-β-D-吡喃葡萄糖苷（3）。
