来自野生雏菊的三萜皂苷。2. 部分脱酰基皂苷的结构。

Triterpenoid saponins from Bellis sylvestris. 2. Structures of partially deacylated saponins.

作者信息

Schöpke T, Hiller K, Wray V, Nimtz M, Yamasaki K, Kasai R

机构信息

Humboldt-Universität zu Berlin, Institut für Pharmazie, Germany. thomas=

出版信息

J Nat Prod. 1996 Apr;59(4):355-9. doi: 10.1021/np9600715.

DOI:10.1021/np9600715

PMID:8699180

Abstract

Four saponins have been isolated from the herbal parts of Bellis sylvestris and the same, together with three further compounds, from the underground parts. The structures were elucidated by electrospray ionization mass spectrometry, including tandem mass spectrometry, and by 1D and 2D homonuclear and heteronuclear NMR spectroscopy. Two of the compounds are new saponins with the structures 3-O-beta-D-glucopyranosyl-2 beta, 3 beta, 23-trihydroxyolean-12-en-28-oic acid 28-O-beta-D-glucopyranosyl (1-->3)-[alpha-L-rhamnopyranosyl (1-->2)]-beta-D- glucopyranoside and 3-O-beta-D-glucopyranosyl-2 beta, 3 beta,16 alpha, 23-tetrahydroxyolean-12-en- 28-oic acid 28-O-alpha-L-rhamnopyranosyl (1-->3)-beta-D-xylopyranosyl(1-->4)-alpha-L- rhamnopyranosyl(1-->2)-[(E)-2-butenoic acid (1-->3)]-beta-D-fucopyranoside. Taxonomically these data provide significant evidence of a link between the Bellis genus and Bellium bellidioides.

摘要

已从林地雏菊的地上部分分离出四种皂苷，从其地下部分分离出同样的四种皂苷以及另外三种化合物。通过电喷雾电离质谱（包括串联质谱）以及一维和二维同核与异核核磁共振光谱对其结构进行了阐明。其中两种化合物是新的皂苷，其结构分别为3 - O - β - D - 吡喃葡萄糖基 - 2β, 3β, 23 - 三羟基齐墩果 - 12 - 烯 - 28 - 酸28 - O - β - D - 吡喃葡萄糖基(1→3)-[α - L - 鼠李吡喃糖基(1→2)] - β - D - 吡喃葡萄糖苷和3 - O - β - D - 吡喃葡萄糖基 - 2β, 3β, 16α, 23 - 四羟基齐墩果 - 12 - 烯 - 28 - 酸28 - O - α - L - 鼠李吡喃糖基(1→3)-β - D - 吡喃木糖基(1→4)-α - L - 鼠李吡喃糖基(1→2)-[(E)-2 - 丁烯酸(1→3)] - β - D - 岩藻吡喃糖苷。从分类学角度来看，这些数据为雏菊属与拟雏菊之间的联系提供了重要证据。