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马里兰州巴尔的摩市阿片类药物成瘾者对美沙酮和丁丙诺啡的滥用。

Uses of diverted methadone and buprenorphine by opioid-addicted individuals in Baltimore, Maryland.

机构信息

Friends Research Institute, Inc., Social Research Center, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.

出版信息

Am J Addict. 2009 Sep-Oct;18(5):346-55. doi: 10.3109/10550490903077820.

Abstract

This study examined the uses of diverted methadone and buprenorphine among opiate-addicted individuals recruited from new admissions to methadone programs and from out-of-treatment individuals recruited from the streets. Self-report data regarding diversion were obtained from surveys and semi-structured qualitative interviews. Approximately 16% (n = 84) of the total sample (N = 515) reported using diverted (street) methadone two-three times per week for six months or more, and for an average of 7.8 days (SD = 10.3) within the past month. The group reporting lifetime use of diverted methadone as compared to the group that did not report such use was less likely to use heroin and cocaine in the 30 days prior to admission (ps <.01) and had lower ASI Drug Composite scores (p <.05). Participants in our qualitative sub-sample (n = 22) indicated that street methadone was more widely used than street buprenorphine and that both drugs were largely used as self-medication for detoxification and withdrawal symptoms. Participants reported using low dosages and no injection of either medication was reported.

摘要

本研究调查了从美沙酮治疗计划新入院者和从街头治疗外的个体中招募的阿片类药物成瘾者中转用美沙酮和丁丙诺啡的情况。关于转用的自我报告数据来自问卷调查和半结构化定性访谈。在总样本(N = 515)中,约有 16%(n = 84)报告说,在过去六个月中,每周使用转用(街头)美沙酮两到三次,过去一个月平均使用 7.8 天(SD = 10.3)。与未报告使用转用美沙酮的组相比,报告终身使用转用美沙酮的组在入院前 30 天内使用海洛因和可卡因的可能性较低(p<.01),且 ASI 药物综合评分较低(p<.05)。我们的定性子样本(n = 22)参与者表示,街头美沙酮的使用比街头丁丙诺啡更为广泛,这两种药物主要被用作自我治疗脱毒和戒断症状的药物。参与者报告使用低剂量,且未报告使用任何药物进行注射。

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