Burstein M, Rubinow A, Shalit M
Hadassah University Hospital, Jerusalem, Israel.
Ann Allergy. 1991 Jan;66(1):36-8.
A middle-aged woman developed recurrent episodes of severe life-threatening anaphylaxis. All episodes were strikingly associated with the first day of menstrual bleeding. Temporary relief was achieved with indomethacin therapy. The patient fully recovered following abdominal hysterectomy and salpingoophorectomy. The possible role of sex hormones and prostaglandin F2 alpha in the pathogenesis of this problem is discussed.
一名中年女性出现反复发作的严重危及生命的过敏反应。所有发作均与月经出血的第一天显著相关。吲哚美辛治疗取得了暂时缓解。患者在接受腹部子宫切除术和输卵管卵巢切除术后完全康复。文中讨论了性激素和前列腺素F2α在该问题发病机制中的可能作用。