George Rachana, Badawy Shawky Z A
Department of Obstetrics and Gynecology, Upstate Medical University, Syracuse, NY 13210, USA.
Case Rep Obstet Gynecol. 2012;2012:757854. doi: 10.1155/2012/757854. Epub 2012 Aug 9.
Background. Autoimmune progesterone dermatitis is a rare cyclic premenstrual allergic reaction to progesterone produced during the luteal phase of a woman's menstrual cycle. Patients present with a variety of conditions including erythema multiforme, eczema, urticaria, angioedema, and progesterone-induced anaphylaxis. Case. Thirty-eight-year-old woman G2P2002 presents with erythema multiforme and urticarial rash one week prior to her menses starting one year after menarche. She was treated with oral contraceptive pills and the symptoms resolved. Conclusion. This is a typical case of progesterone autoimmunity. The diagnosis is based on cyclic nature of the dermatitis. This differentiates the condition from other allergies or systemic diseases with skin manifestations. Inhibition of ovulation in such cases results in decrease in progesterone secretion and prevention of symptoms.
背景。自身免疫性孕酮性皮炎是一种罕见的、在女性月经周期黄体期对孕酮产生的周期性经前过敏反应。患者会出现多种病症，包括多形红斑、湿疹、荨麻疹、血管性水肿以及孕酮诱导的过敏反应。病例。一名38岁女性，孕2产2（G2P2002），月经初潮后一年，在月经开始前一周出现多形红斑和荨麻疹样皮疹。她接受了口服避孕药治疗，症状得以缓解。结论。这是一例典型的孕酮自身免疫病例。诊断基于皮炎的周期性特点。这将该病症与其他有皮肤表现的过敏或全身性疾病区分开来。在此类病例中抑制排卵会导致孕酮分泌减少并预防症状。
