Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria, Australia.
J Arthroplasty. 2010 Dec;25(8):1216-22.e1-3. doi: 10.1016/j.arth.2009.08.011. Epub 2009 Oct 30.
Although deep surgical site infection (SSI) is a major complication of primary total hip arthroplasty (THA), there are conflicting data regarding the incidence of deep SSI, and no comprehensive evaluation of the associated risk factors has been undertaken. We performed a systematic review of the literature; undertaking computer-aided searches of electronic databases, assessment of methodological quality, and a best-evidence synthesis. The incidence of SSI ranged from 0.2% before discharge to 1.1% for the period up to and including 5 years post surgery. Greater severity of a pre-existing illness and a longer duration of surgery were found to be independent risk factors for deep SSI. There is a need for high-quality, prospective studies to further identify modifiable risk factors for deep SSI after THA.
虽然深部手术部位感染（SSI）是初次全髋关节置换术（THA）的主要并发症，但深部 SSI 的发生率存在争议，且尚未对相关危险因素进行全面评估。我们对文献进行了系统回顾，通过计算机辅助检索电子数据库、评估方法学质量，并进行最佳证据综合。SSI 的发生率从出院前的 0.2%到手术后 5 年内的 1.1%不等。术前疾病的严重程度较高和手术时间较长被认为是深部 SSI 的独立危险因素。需要高质量的前瞻性研究来进一步确定 THA 后深部 SSI 的可改变危险因素。
