Germain D
Université Claude-Bernard Lyon-I, 8, avenue Rockefeller, 69008 Lyon, France.
Pathol Biol (Paris). 2009 Nov-Dec;57(7-8):555-9. doi: 10.1016/j.patbio.2009.09.017. Epub 2009 Oct 31.
There is less than three years, the reprogramming of adult cells in induced pluripotent stem cells (iPS cells) has been added to the techniques producing natural or manufactured embryonic cells. Easier to obtain than these last, the human iPS cells are ethically irreproachable. They allow the study of many disorders at the cellular level and put at the disposal of pharmacologists a material of an exceptional interest. The improvement of the quality of their reprogramming is the object of active search all over the world. It is not utopian to hope that the iPS cells will quickly take a choice place in human cellular therapy.
在不到三年的时间里，诱导多能干细胞（iPS细胞）中成年细胞的重编程已被纳入生产天然或人工胚胎细胞的技术之中。人类iPS细胞比后者更容易获得，在伦理上无可指责。它们有助于在细胞水平上研究多种疾病，并为药理学家提供了一种极具价值的材料。提高其重编程质量是全球积极探索的目标。希望iPS细胞能很快在人类细胞治疗中占据一席之地并非空想。
